por Pall Biotech 31 de agosto, 2018
< Volver

Continuous bioprocessing initiatives have accelerated in recent years. The transition from batch to continuous bioprocessing offers numerous advantages, including process time savings and lower capital costs due to smaller equipment, tanks, and tubing sizes. Additionally, hold tanks may no longer be needed between unit operations, which can be especially valuable for facilities with limited manufacturing floor space. Furthermore, reduced system hold-up volumes improve product recoveries and also contribute to the smaller system footprint of continuous bioprocessing systems.

Continuous bioprocessing solutions were initially developed for upstream processes (i.e. perfusion bioreactors), but continuous downstream unit operations have recently progressed as well. One unit of operation that is especially beneficial for continuous bioprocessing initiatives is the ultrafiltration (UF) step, which can be accomplished through the use of Pall’s patented single-pass tangential flow filtration (SPTFF) technology [1,2,3,4]. SPTFF eliminates the conventional TFF recirculation loop and utilizes a staged flow path design, allowing concentrations of 2 to 30X to be achieved continuously in a single-pass through the module. The single pump pass reduces minimum working volume concerns and is ideal for processing of fragile biomolecules.

Publicidad

Noticias relacionadas

comments powered by Disqus

Utilizamos cookies propias y de terceros para analizar nuestros servicios y mostrarle publicidad relacionada con sus preferencias en base a un perfil elaborado a partir de sus hábitos de navegación (por ejemplo, páginas visitadas o videos vistos). Puedes obtener más información y configurar sus preferencias.

Configurar cookies

Por favor, activa las que quieras aceptar y desactiva de las siguientes las que quieras rechazar. Puedes activar/desactivar todas a la vez clicando en Aceptar/Rechazar todas las cookies.

Aceptar/rechazar todas
Cookies Analíticas

Cookies que guardan información no personal para registrar información estadística sobre las visitas realizadas a la web.

Cookies de Marketing

Cookies necesarias para determinadas acciones de marketing, incluyendo visualización de vídeos provenientes de plataformas como Youtube, Vimeo, etc. y publicidad de terceros.

Cookies de Redes Sociales

Cookies relacionadas con mostrar información provenientes de redes sociales o para compartir contenidos de la web en redes sociales.